Myocardial bridges: From incidental findings to myocardial ischemia
نویسندگان
چکیده
منابع مشابه
Myocardial Ischemia
Difficulties in studying myocardial metabolism with adequate time resolution have led to contradictory conclusions regarding the mechanisms causing contractile abnormalities during the early stages of ischemia. In acutely instrumented swine, we investigated whether abnormalities in subendocardial ATP, phosphocreatine, or lactate content develop rapidly enough during the first few heart beats af...
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Regional myocardial blood flow and contractile function in ischemic myocardium are well matched, and there is no evidence for an oxygen supply/demand imbalance. Thus, myocardial ischemia is lack of coronary blood flow with electric, functional, metabolic, and structural consequences for the myocardium. All therapeutic interventions must aim to improve blood flow to ischemic myocardium as much a...
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It has been recognised for over 200 years that epicardial coronary arteries may be crossed by muscular bands for limited segments of their courses. The term myocardial bridge was first employed in 1961 in a case report describing angiographic systolic narrowing. Opinion remains divided as to whether myocardial bridges have pathological consequences or are merely epiphenomena. The clinical conse...
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Organ damage after reperfusion of previously viable ischemic tissues is defined as ischemia/reperfusion injury. The pathophysiology of ischemia/reperfusion injury involves cellular effect of ischemia, reactive oxygen species and inflammatory cascade. Protection against ischemia/reperfusion injury may be achieved by preconditioning or postconditioning. In this review, we discuss basic mechan...
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The effects of inosine (INO) on substrate metabolism and rigor formation in ischemic myocardium were examined in isolated rabbit hearts. Metabolite content was assessed in tissue extracts by chemical analysis and in the whole heart by `C and 31P nuclear magnetic resonance spectroscopy. In ischemic hearts metabolizing either [3-'3Clpyruvate or [1-13C glucose, 1 mM INO increased both total and D3...
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ژورنال
عنوان ژورنال: Srce i krvni sudovi
سال: 2013
ISSN: 1821-4835
DOI: 10.5937/siks1302110a